Stem Cells

Stem cells are the master cells of our body. Stem cells are characterized dependent on two major characteristics, long time self-renewal capacity even after inactive for a longer period and differentiation ability (one or more different specialized cell types). The totipotent Stem cells have the potential to frame a wide range of tissues and organs in the developing life and additional embryonic tissues. Tissue-specific cells present in various niches in our body like bone marrow, brain, liver, umbilical cord, adipose tissue, dental pulp, and skin. The main function and activity of stem cells were mainly tissue maintenance (including growth, repair). Adult stem cell showed plasticity towards some specific lineages

Stem cells have 3 different types.

  1. Embryonic Stem Cells
  2. Induced Pluripotent Stem Cells
  3. Adult Stem cell

Adult Stem cells are unique human cells that can form into various cell types, from muscle cells to nerves. Now and again, they have the ability to repair damaged tissues. Stem cells can generate cells to replace those that are lost through normal repair, disease, or injury. Stem cells are found throughout one’s lifetime in tissues such as the umbilical cord, placenta, tooth, Adipose tissue and bone marrow. The first adult stem cells were extracted and used for blood production in 1948.

Adult stem cells are categorized into two types.

  1. Hematopoietic Stem Cells (Blood Stem Cells)
  2. Mesenchymal Stem Cells (Tissue Stem cells)

Hematopoietic stem cells are available from two major sources,they are bone marrow and umbilical cord blood. Mesenchymal stemcells are available from bone marrow, umbilical cord tissue, dental pulp, and adipose tissue.

Mesenchymal stem cells have the potential to develop into structural and connective tissues in our body. Because of this character,mesenchymal stem cells could potentially be used in treating more disease conditions than blood stem cells. Research in the mesenchymal stem cell area is now the forefront of medical sciences.” Incurable” conditions were targeted with cellular approaches.

dental stem cell banking

Dental Stem cells

Stem cells found in the tooth pulp are called dental stem cells. The dental pulp stem cells are found within the child’s milk teeth and healthy adult teeth. These cells have remarkable regenerative potential and can convert into different types of cells. Tooth derived cells are considered to be naive cells which allow these cells to adapt and repair cells like muscles, nerves,joints and even a damaged heart. The tooth pulp is an extremely good source for the mesenchymal stem cells. Mesenchymal stem cells have the ability to eventually form dentin, enamel, nerves tissues, blood vessels, and dental pulp. Because of extreme ease in the collection in younger years of age before calcification, and minimal to no morbidity, they constitute a major source for personal banking, research, and multiple other therapeutic applications. These dental pulp/ mesenchymal stem cells shown capable of producing hepatocytes and beta cells this may be a potential cure for liver cirrhosis and diabetes in the future.

Mesenchymal stem cells harvested from the dental pulparea powerful and potent platform for developing cellular treatments in the future. Different groups of scientific communities are studying the role of these amazing cells in treating conditions such as type 1 diabetes, spinal cord injury, stroke, myocardial infarction (heart attack), corneal damage and neurological diseases like Parkinson's, etc. By preserving our own teeth stem cells or child’s teeth we ensure our future. Wisdom teeth also one of the best viable sources of dental stem cells. If someone lost the opportunity to store stem cell at the time of birth (umbilical cord) now they have another opportunity to preserve these viable dental pulp stem cells from the teeth. The hematopoietic stem cells obtained from umbilical cord that can just create in the blood & immune system-related area cells, MSCs got from teeth have boundless potential because of their pluripotency. Mesenchymal stem cells hold the promise regenerating damaged organs/ tissues to re-establish the normal function of those specific organs/ tissues by stimulating the body's own repair mechanisms to heal previously irreparable organs/ tissues.

Mesenchymal stem cells decline with age

Traditionally bone marrow is a very rich source for hematopoietic stem cells whereas it's not that great source for mesenchymal stem cells. MSCs availability drastically reduces in the bone marrow when the age of an individual increase. Researchers state mesenchymal stem cells decline with age. As illustrated in the below graph, per marrow we can found ONE mesenchymal stem cell in every 10,000 cells when the child is under 11 years. When the child's age becomes 18 plus years, the availability of mesenchymal stem cells goes down 10 times and we can only found 1 mesenchymal stem cell in every 1,00,000 cells and so on.. Therefore preserving mesenchymal stem cells from the dental pulp during the younger ages of the child is the best opportunity for the parents.

Mesenchymal stem cells

10 Reasons to store your child's dental pulp stem cells today

  1. Banking stem cells at the age of 5-11 years means they are available anytime throughout your children’s lifespan. Whenever they need it in the future, there is no need to identify a suitable match and no necessity or hassle to search. They can directly use them from the bank.
  2. Stem cells are building blocks of our body. All the organs and tissues in the human body are made up of these stem cells. Clinicians use them to regenerate the damaged organs/ tissues. By preserving these stem cells scientifically, you can treat life-threatening degenerative conditions effectively.
  3. Younger the stem cells the more the effectiveness. Before they can deteriorate with age, store your child’s tooth stem cells today.
  4. Thousands of ongoing registered clinical trials and researches are being done to assess future medicine applications using the potential of stem cells with Parkinson’s, Stroke, Diabetes Type – I, Muscular Dystrophy, Ophthalmology conditions, cartilage regeneration, etc.
  5. Harvesting Mesenchymal stem cells from the milk tooth are the best way to obtain Mesenchymal stem cells without any pain/ invasive procedures.
  6. Tooth pulp Stem cells have more potential for addressing untreatable medical conditions compared with other stem cell sources.
  7. When Compared with Bone marrow transplantation tooth stem cells banking is less expensive and pains less.
  8. Mesenchymal stem cells derived from your child’s dental pulp have the most perfect match cells for themselves. They have NO chances of rejection and contracting other diseases because these cells are derived from the child’s own natural part.
  9. Personalized Stem Cell-based medicine is going to be the Face of the future Medicine and Mesenchymal stem cells stored from your child's milk tooth will be handy to complete the personalized stem cell product.
  10. Since the tooth is from the Ecto-lineage of the human body, Mesenchymal stem cells derived from the tooth are considered more effective in addressing Ecto-lineage degenerative conditions like Sensory organs related degenerative issues, neurological disorders, brain nerves, etc.